SANTA CLARA, TEXAS. Santa Clara was nine miles southwest of Seguin and one mile south of Interstate Highway 10 in southwestern Guadalupe County. In 1904 Santa Clara had a one-teacher school for thirty-two students. In addition to the school, there were a few scattered houses in the area in 1946; by the mid-1980s, only a church and a cemetery marked the location of the community on county highway maps. The population was 889 in 2000.
