Harry Wyse Brown, physician, was born in Savannah, Georgia, on October 20, 1827, the son of Robert Cuthbert and Mary Lowe (Clark) Brown. He studied medicine under Robert A. T. Gridley at La Grange, Georgia, at the College of Physicians and Surgeons in New York from 1845 to 1847, and at the University of New York in 1847–48. He graduated from Bellevue Hospital Medical College in May 1848. He practiced in Griffin and Atlanta, Georgia, before 1856, when he became professor of chemistry and anatomy in the Atlanta Medical College. He became a surgeon in the Confederate Army in 1861 and served in hospitals in Columbus, Mississippi, and in Atlanta, Macon, Augusta, and Madison, Georgia. At the end of the war he moved to Belton, Texas, and in 1868 to Waco. He was president of the Waco Medical Society, vice president of the American Medical Association, and president of the Texas State Medical Association in 1875–76 (see TEXAS MEDICAL ASSOCIATION). Brown married Mary Eaton Smith of Gallatin, Tennessee, in 1849, and they had four children. He died in Waco at the home of one of his daughters on November 26, 1907.