The Coapite (Coapiste, Guapica, Guapite) Indians were Karankawans who, when first reported by this name in the eighteenth century, lived on the Texas coast near Matagorda Bay, where they were closely associated with the Cujanes and Karankawas proper. In 1722 Espíritu Santo de Zuñiga Mission was established for these Indians near Matagorda Bay, but hostilities between Spaniards and Indians soon led to its removal. In 1754 the Spanish again attempted to missionize the Coapites and their Karankawan associates by establishing Nuestra Señora del Rosario Mission near the site of future Goliad. The Coapites were periodically in and out of this mission until as late as 1831. During this period a few Coapite Indians entered Nuestra Señora de la Purísima Concepción de Acuña Mission at San Antonio. Some of the Coapites also entered Nuestra Señora del Refugio Mission when it was founded in 1793 and were reported as being there until 1828. After this, remnants of the Coapite Indians seem to have merged with the group known to the Anglo American settlers as Karankawas, who disappeared in the middle of the nineteenth century.