Francis (Frank) Marion Hopkins, early Red River County settler, was born in Kentucky before 1795. From about 1811 until the early 1820s he lived in Indiana. With his first wife, Hopkins had six children, including James E. and Richard M. Hopkins. After his wife's death in Indiana he married Sophia Gudgiel, with whom he apparently had no children. Around 1823 he moved to Texas with his family and a number of friends intending to join Austin's colony. The group stopped to raise a crop at the Burkham Settlement, near the mouth of Mill Creek in what became Red River County, and elected to settle there permanently. Hopkins was active in local affairs and played an important role in helping to develop the region. In 1830 he signed a petition requesting "a good and passable road" for settlers east of Jonesborough in the Sevier township.