Isaac Low, Sabine County pioneer, was born on July 7, 1781, probably near Knoxville, Tennessee. He married Elizabeth Parsons on September 25, 1804, in Tennessee, and they had twelve children. The family moved to Sabine County, Texas, in August 1828. In 1835 Low received a league and a labor of land from the Mexican government. He operated a ferry on this grant, on the Sabine River near the mouth of Lows Creek. It is alleged that there during the Runaway Scrape he and his older sons worked day and night for several days ferrying panic-stricken settlers back to the United States. The site is now under the waters of Toledo Bend Reservoir. In 1840 Low served as a commissioner of Sabine County, investigating fraudulent land certificates; he may have held other civil jobs in the county. He died on August 27, 1853, at his home near Sabinetown, Texas, and was buried in the old Isaac Low Cemetery, now near the shore of Toledo Bend Reservoir.