Mildred Mayhall, historian, writer, and teacher, the daughter of David Jones and Birdie Mildred (Givens) Pickle, was born in Austin, Texas, on December 20, 1902. She attended Austin public schools and the National Park Seminary in Washington, D.C. She received the B.A. (1924), M.A. (1926), and Ph.D. (1939) degrees from the University of Texas. Although trained as a historian, she taught anthropology at the University of Texas for twenty years before taking a position as a history teacher at Stephen F. Austin High School in Austin.
She was the author of two studies of Indians, The Kiowas (1962) and Indian Wars of Texas (1965). She served as a consultant for Time-Life Books for The Great Chiefs (1975) in the series The Old West. She also wrote numerous articles for various historical magazines. At Austin High School she served as faculty sponsor for the Junior Historians. She was active in the Texas State Historical Association and the Daughters of the American Revolution.
Mayhall was an amateur horticulturist who was interested in rose culture and developed several new strains of rose. She published a book on rose culture and wrote the descriptive material for Eliza Griffin Johnston's Texas Wild Flowers (1972). Mayhall helped organize the Austin Rose Society and was an early member of the Violet Crown Garden Club.
She married Temple B. Mayhall, an architect, on September 12, 1925. They had three sons, one of whom died in infancy. Mildred Mayhall was a member of the United Methodist Church of Austin. She moved to Salem, Oregon, shortly before her death on April 19, 1987. She is buried in Oakwood Cemetery, Austin.