John Woodruff Mayrant, Confederate officer, was born in South Carolina on May 10, 1826, to Dr. James Norvell Mayrant and Mary Elizabeth (Potts) Mayrant. Prior to 1860 Mayrant married Abyssinia "Simmie" Kelen Potts and relocated to Grayson County, Texas. There, the couple had one son and four daughters.
At the beginning of the Civil War, Mayrant enlisted as a lieutenant in the Eleventh Texas Cavalry Regiment, then forming in Grayson County. On August 5, 1861, he received promotion to major. When the Eleventh Cavalry underwent reorganization in May 1862, Mayrant was dropped from the unit's roster of officers. After the war, he resided with his wife in Preston Bend, Texas. Mayrant died on September 30, 1879. Mayrant and his wife are buried in Mayrant–Potts Cemetery in Preston Bend.