Fernando Pérez de Almazán was emissary to the French commander at Natchitoches on the occasion of the Aguayo expedition and was appointed governor of Texas as a result of the Marqués de Aguayo's proposal in 1720 that Coahuila and Texas have separate governments. When the appointment was confirmed by the viceroy in 1722, the new governor established his capital at Los Adaes. Crop failures in East Texas in 1724 forced him to seek supplies in San Antonio. He facilitated travel by placing rafts at the difficult river crossings. In 1725 ill health induced him to remain in San Antonio and appoint Captain Mediavilla of Los Adaes as lieutenant governor. Sometime between 1727 and 1729 Pérez de Almazán resigned his office because of ill health and was in Mexico City in 1729. It was during his administration that Pedro de Rivera y Villalón inspected the presidios of Texas and undid some of Aguayo's work by having the presidios near Nuestra Señora de la Purísima Concepción de Acuña Mission in East Texas closed. This entailed the closing of the three nearby Queretaran missions, their so-called transfer to the Colorado River in 1730, and their reestablishment on the San Antonio River in 1731.